Abstract
Novel Prion Protein in BSE-affected Cattle, Switzerland
Highlights
To the Editor: Bovine spongiform encephalopathy (BSE) is a feed-borne prion disease that affects mainly cattle and other ruminants, felids, and humans [1]
In accordance with the guidelines of the World Organisation for Animal Health [5], BSE was confirmed for each animal by positive test results in independent, approved screening tests, of which 1 must be a Western blot
AJ298878) and was not likely to account for the differences observed by Western blot testing
Summary
To the Editor: Bovine spongiform encephalopathy (BSE) is a feed-borne prion disease that affects mainly cattle and other ruminants, felids, and humans [1]. In accordance with the guidelines of the World Organisation for Animal Health [5], BSE was confirmed for each animal by positive test results in independent, approved screening tests, of which 1 must be a Western blot The Prionics Western blot detected a similar 3-band PrPres glycoprofile with molecular masses of roughly 16, 20, and 25 kDa for each animal, lower than equivalent PrP Protein bands detected in animals with C-BSE (Figure).
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