Abstract
Two novel coumarin-based pyrazoline derivatives have been designed and synthesized as organogel factors. Organogelators Z 1–2 both have gelation behavior in alcohol solution and DMSO. Gel- tert -butanol Z 1–2 (CGC = 1.84%, 1.41%) fluoresce blue and yellow-green under ultraviolet irradiation, respectively. Z 1–2 both exhibit selectivity for response to Fe 3+ in THF-deionized aqueous (V: V = 9:1) solution, meanwhile display high sensitivity. Notably, introducing diethylamino at 7-position the coumarin unit increases the detection line range in Z 2 . Furthermore, Z 2 not only has a good biocompatibility in living cells but also the sensing behavior of Fe 3+ in the cell nucleus. The coordination mechanism of gelators Z 1–2 and Fe 3+ were performed at the DFT level. • Two novel coumarin-based pyrazoline organogelators Z 1–2 have designed and synthesized. • The Z 1–2 can both form fluoresce organogels in tert-butanol (CGC=1.84%, 1.41%). • The Z 1–2 can both response to Fe 3+ in aqueous solution and organogels with selectivity and sensitivity. • The Z 2 can detect Fe 3+ in living cells.
Published Version
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