Abstract

AbstractNovel chiral amide host compounds (2−8) have been synthesized from mandelic acid (1). A marked difference between the inclusion properties of analogous isomers such as 5 and 6 was observed. Host compounds 4 and 5 showed a relatively high chiral recognition in the optical resolution of guest compounds by inclusion crystallization. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)

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