Novel case of ELANE-related severe congenital neutropenia with initially normal bone marrow.

Abstract

Pediatric Blood & CancerEarly View e30468 LETTER TO THE EDITOR Novel case of ELANE-related severe congenital neutropenia with initially normal bone marrow Camille Keenan, Corresponding Author Camille Keenan [email protected] orcid.org/0000-0001-9693-9917 Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA Correspondence Camille Keenan, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Mail Stop 343, Memphis, TN, 38105, USA. Email: [email protected]Search for more papers by this authorMichelle Boals, Michelle Boals Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USASearch for more papers by this authorSara Lewis, Sara Lewis Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USASearch for more papers by this authorGabriela Gheorghe, Gabriela Gheorghe Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USASearch for more papers by this authorRohith Jesudas, Rohith Jesudas Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USASearch for more papers by this author Camille Keenan, Corresponding Author Camille Keenan [email protected] orcid.org/0000-0001-9693-9917 Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA Correspondence Camille Keenan, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Mail Stop 343, Memphis, TN, 38105, USA. Email: [email protected]Search for more papers by this authorMichelle Boals, Michelle Boals Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USASearch for more papers by this authorSara Lewis, Sara Lewis Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USASearch for more papers by this authorGabriela Gheorghe, Gabriela Gheorghe Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USASearch for more papers by this authorRohith Jesudas, Rohith Jesudas Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USASearch for more papers by this author First published: 08 June 2023 https://doi.org/10.1002/pbc.30468Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. REFERENCES 1Gong RL, Wu J, Chen TX. Clinical, laboratory, and molecular characteristics and remission status in children with severe congenital and non-congenital neutropenia. Front Pediatr. 2018; 6: 305. 2Zeidler C. Congenital neutropenias. Hematology. 2005; 10(Suppl 1): 306- 311. 3Welte K, Zeidler C, Reiter A, et al. Differential effects of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in children with severe congenital neutropenia. Blood. 1990; 75(5): 1056- 1063. 4Boxer LA. How to approach neutropenia. Hematology Am Soc Hematol Educ Program. 2012; 2012: 174- 182. 5Skokowa J, Dale DC, Touw IP, Zeidler C, Welte K. Severe congenital neutropenias. Nat Rev Dis Primers. 2017; 3:17032. 6Rezaei N, Moin M, Pourpak Z, et al. The clinical, immunohematological, and molecular study of Iranian patients with severe congenital neutropenia. J Clin Immunol. 2007; 27(5): 525- 533. 7Makaryan V, Zeidler C, Bolyard AA, et al. The diversity of mutations and clinical outcomes for ELANE-associated neutropenia. Curr Opin Hematol. 2015; 22(1): 3- 11. 8Newburger PE, Pindyck TN, Zhu Z, et al. Cyclic neutropenia and severe congenital neutropenia in patients with a shared ELANE mutation and paternal haplotype: evidence for phenotype determination by modifying genes. Pediatr Blood Cancer. 2010; 55(2): 314- 317. 9Dale DC, Bonilla MA, Davis MW, et al. A randomized controlled phase III trial of recombinant human granulocyte colony-stimulating factor (filgrastim) for treatment of severe chronic neutropenia. Blood. 1993; 81(10): 2496- 2502. 10Pietsch T, Bührer C, Mempel K, et al. Blood mononuclear cells from patients with severe congenital neutropenia are capable of producing granulocyte colony-stimulating factor. Blood. 1991; 77(6): 1234- 1237. Early ViewOnline Version of Record before inclusion in an issuee30468 ReferencesRelatedInformation