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https://doi.org/10.1021/co200072z
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Cite Journal: ACS Combinatorial Science |  Publication Date: Jun 27, 2011 |
 Citations: 49 |
Affiliation: University of Genoa, Merck Serono (Switzerland)
α-Azido aldehydes can be employed in Passerini reactions with isocyanides and various propiolic acids to afford the three-component adducts in moderate to good yields. These compounds undergo a straightforward azide-alkyne dipolar cycloaddition to furnish triazolo-fused dihydrooxazinones.
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