Abstract
A simple method for the generation of three novel linkers, alpha-hydroxyethyl-polystyrene, alpha-chloroethyl-polystyrene and alpha-amino-oxyethyl-polystyrene on Multipin supports (SynPhase Crowns) has been developed. Applications of these linkers have been successfully demonstrated for solid-phase synthesis of dipeptide, oxime, and hydroxamic acid compounds in good yields and purities.
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