Abstract

A simple method for the generation of three novel linkers, α-hydroxyethyl-polystyrene, α-chloroethyl-polystyrene and α-amino-oxyethyl-polystyrene on Multipin supports (SynPhase™ Crowns) has been developed. Applications of these linkers have been successfully demonstrated for solid-phase synthesis of dipeptide, oxime, and hydroxamic acid compounds in good yields and purities. © 2000 John Wiley & Sons, Inc. Biotechnol Bioeng (Comb Chem) 71:91–93, 2000/2001.

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