Abstract
Urinary bone resorption marker, deoxypyridinoline (DPD), and serum bone formation marker, bone alkaline phosphatase (BAP), were determined in three cases of osteoporotic patients with alendronate therapy. DPD decreased significantly at 1 month after start of treatment in two cases, and at 2 months in the other case. BAP gradually decreased by 30-40% at 3 months in all cases. The result shows that the determination of bone markers is useful for drug selection and early assessment of treatment efficacy in osteoporosis.
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