Nosocomial pneumonia with multi-resistant bacteria in the intensive care units

Abstract

A nosocomial pneumonia is a pulmonary infection occurring in a patient after 48 hours of care in a health care facility, it is an infection that is serious because it is often due to multi-resistant germs called multi-resistant bacteria. The objective of our study is to analyze the bacterial ecology of nosocomial pneumopathies in intensive care units and their evolution between January 1st 2021 and December 31st 2021. We conducted a monocentric retrospective study in the microbiology laboratory of the CHU HASSAN II of Fez. We analyzed all the respiratory microbiological diagnostic samples taken during this period (identified germ, sensitivity profile), and collected the demographic characteristics of the associated population. Out of 192 respiratory samples received, 106 were multidrug resistant bacteria (52.6%). The proportions of the different bacterial classes (BGN / CG+) have remained stable over the last 4 years with a predominance of Acinetobacter baumanii with 93%, followed by Klebsiella pneumoniae (4.7%) and Escherichia coli (2.83%)..Bacteria of clinical interest showed increasingly worrying levels of resistance to beta-lactam antibiotics, with the exception of methicillin-resistant Staphylococcus aureus, which remained stable between 2018 and 2021.This work is part of a process of improving antibiotic prescribing practices and analyzing the impact of changes in antibiotic therapy protocols on the ecology of the service.