Abstract
Oral feeding of sodium glycolate (50 mg/d/rat for ten days) caused a significant ( P < 0.001) increase in oxalate and taurine excretion and a decrease in liver protein content ( P < 0.05), glycolic acid oxidase levels ( P < 0.01), and glycolic acid dehydrogenase levels ( P < 0.01) as compared to normal untreated rats. Taurine (100 mg/d/rat), when administered along with glycolate, prevented these effects of glycolate as evident from normal urinary excretion of oxalate, liver protein content, glycolic acid oxidase, and glycolic acid dehydrogenase levels in glycolate-plus taurine-fed animals.
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