Noonan Sendromu Olan Çocuklarda Ses Özellikleri

Abstract

Objective: Noonan syndrome (NS) is characterized by multiple physical and cardiac anomalies. Voice characteristics in NS are not well characterized in the available literature. The aim of this study was to examine voice properties of patients with NS. Material and Methods: This study included 11 children with NS with a mean age of 11.96±3.47 years (age range: 6.3-17.7). The control group consisted of 11 healthy children with a mean age of 11.96±3.34 years (age range: 6.0-17.1). In all subjects (n=22), 11 parameters out of 33 acoustic parameters of the Multi-Dimensional Voice Program, related to fundamental frequency, frequency variations, amplitude variations, and noise measurements were analyzed. Results: In the acoustic analysis of children with NS, soft phonation index (SPI) was found to be lower than that in the control group (p<0.05). Fundamental frequency of children with NS was higher than that in the control group; but the difference was not statistically significant (p>0.05). Conclusion: This study adds knowledge about the clinical symptoms of children with NS. The findings of this study indicate that children with NS mostly share similar voice properties with healthy children.