Abstract
ABSTRACTNecrotizing sialometaplasia (NS) is a benign, self-limiting inflammatory entity that mainly affects the minor salivary glands located in the hard palate. Classically, NS is characterized as a nodule that evolves to a central ulcer. The most widely recognized triggering factor is an ischemic event. The diagnosis becomes a challenge in non-ulcerated NS cases which is essential to rule out the possibility of salivary gland tumors, especially the malignant ones. Here, we presented a case of a 32-year-old male patient with a 1-month complaint of a painful, slightly elevated erythematous area on the hard palate. Incisional biopsy was performed, and NS was diagnosed based on histopathological and immunohistochemical analyses. Clinicians should be aware of and consider NS as a differential diagnosis of minor salivary gland tumors, particularly when it presents as a non-ulcerated clinical aspect.
Highlights
The hard palate harbors several minor salivary glands, which are the main structures affected by pathological changes in the palate
Necrotizing sialometaplasia (NS) is a well-described inflammatory disease that in most cases affects the minor salivary glands located in the hard palate
NS is a rare condition, with just over 200 cases reported in the English language literature.[2]
Summary
Patrícia Maria Fernandes[1 ], Erika Graf Pedroso[1], Alan Roger Santos-Silva[1 ], Pablo Agustin Vargas[1 ], Márcio Ajudarte Lopes[1].
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