Non-thermal stress-induced modifications of fatty acids profiles in rat brown adipose tissue

Abstract

1. 1.|The changes in fatty acids (FA) composition were studied in triglyceride and phospholipid fractions of interscapular brown adipose tissue (BAT) in cold-acelimated (5°C, 4 wk) (CA), repetitively immobilized (3 hr/day, 4 wk) (IM) and treadmill-running trained (T) (30 m/min, 30 min/day under 8° inclination, 4 wk) rats. 2. 2.|Fatty acids composition in triglyceride: in CA rats the saturated FA (SA) and polyunsaturated FA (PU) were higher, while monounsaturated FA (MU) was lower. In IM rats SA was lower, while MU and PU were higher. Unsaturation index (UI) and PU/SA were higher in IM rats. In T rats SA and MU were lower, while PU was higher, UI and PU/SA were higher in T rats. 3. 3.|Fatty acids composition in phospholipid: in CA rats SA and PU were higher, while MU was lower. UI and PU/SA were higher. In IM rats SA and MU were lower, while PU was higher. UI and PU/SA were higher. In T rats MU was lower, but no changes were observed in UI and PU/SA. 4. 4.|These findings have indicated that non-thermal stress such as immobilization caused similar changes in FA composition of rat BAT, especially an increase in the extent of unsaturation in FA of phospholipid, to those previously reported and presently confirmed in CA animals. On the other hand, exercise training did not affect the extent of unsaturation in FA of phospholipid as assessed by UI and PU/SA.