Abstract

In addition to being the main cause of death and premature mortality in Europe, cardiovascular diseases are increasingly becoming a significant burden on public health, productivity and healthcare resources. At 34 %, coronary heart disease (CHD) represents the largest proportion of this spectrum (1). The traditional understanding of CHD, which focused almost exclusively on epicardial atherosclerotic stenoses, is now considered outdated. Although increasing attention is being paid to non-obstructive CAD, the mechanisms are largely unknown and the diagnosis may be underestimated in everyday practice. Therefore, itis crucial to recognize non-obstructive CHD in order to develop appropriate treatment strategies. The aim of this review is to provide an overview of the common definitions, causes and diagnostic steps of non-obstructive coronary artery disease.

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