Abstract
Chalcones are significant entities in the synthetic pathway of several heterocyclic molecules and well-known moiety for its versatile biological and pharmacological activities e.g., anticancer, antioxidant, anti-inflammatory, antimicrobial, antiallergic, and antimalarial activities etc. The chemical structure of chalcone comprises open chain flavonoids, where α, β unsaturated carbonyl, having three carbons, motif links two rings who are aromatic in nature. α, β unsaturated keto group present in chalcones are responsible for their diverse antimicrobial activity.A huge amount of research is done on the biological activity of chalcones and very few material properties of chalcone are explored. Among the material properties, one of the most interesting properties is its nonlinear optical properties. The exploration started long back in the nineties century and a review would clear the picture of the present scenario of where we were and where we can head with the nonlinear properties of chalcone derivatives.The design strategy obtained from the review of the past research work shows that chalcone core is a useful NLO chromophore. For bridging/ linking moiety, an alkene-bridge has been found to be more effective link compared to an alkyne-bridge. The higher degree of conjugation, which is an inherent property of ethylene-linked π systems is found to be the reason behind its effectiveness. Dialkyl and diaryl donors have been found more effective than oxygen-based donors, phenoxide is the strongest donor. D-π-D and D-π-A-π-D are significantly operative than A-π-A and A-π-D-π-A. Conjugation Signature (Sc) is the measure of effective conjugation length. Rigid conformations of π bridge systems are more effective than flexible ones.
Published Version
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