Abstract

Understanding the behavior of cavitation bubbles driven by ultrasonic fields is an important problem in biomedical acoustics. The previous studies are largely limited by availability of experimental data on soft tissue. To approach this problem, we combine the Keller-Miksis equation for nonlinear bubble dynamics with the linear Voigt model for viscoelastic media. Using experimentally determined values of viscoelastic properties of soft tissue as a guide, the effects of elasticity on bubble oscillations are studied. The inertial cavitation thresholds are determined using a criterion of Rmax/R0=2, and subharmonic emissions from an oscillating bubble are calculated. The results show that the presence of the elasticity increases the threshold pressure for inertial cavitation, and subharmonic signals only can be detected in a certain region of radii and driving pressures at a given frequency. These results should be useful in cavitation detection and bubble-enhanced imaging work. The model also could be used to determine values for the viscoelastic properties of soft tissue.

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