Abstract
Objective. To explore the use of the noninvasive high-frequency oscillatory ventilation and CPAP ventilation mode in the treatment of neonatal respiratory distress syndrome and to compare the treatment effect and the incidence of complications and whether it can reduce the time to go to the hospital and the number of hospital stays. Methods. Seventy-four children with RDS treated in hospital were selected and divided into the noninvasive high-frequency group (NHFV group, 36 children) and noninvasive positive pressure ventilation group (NCPAP group, 38 cases), and they were compared with the changes in arterial blood gas, the occurrence of complications, and the time on the machine before and after the operation on 12, 24, 48, and 72 hours. Results. In the NHFV group, PO2, a/APO2, and SaO2 were higher than those in the NCPAP group at 12, 24, 48, and 72 h after the respiratory support was given, and the differences were statistically significant (all P < 0.05 ). PaCO2 in the NHFV group was given respiratory support. After support, the results at 12, 24, 48, and 72 h were lower than those in the NCPAP group, and the difference was statistically significant (both P < 0.05 ). The children in both groups were cured and discharged from the hospital, with air leakage, persistent pulmonary hypertension, and bronchopulmonary dysplasia; there were no statistically significant differences in the incidence of complications such as retinopathy, pulmonary hemorrhage, and intracranial hemorrhage ( P > 0.05 ). The NHFV group had less tracheal intubation, operation time, and hospital stays than the NCPAP group. The differences were significant. Statistical significance was at P < 0.05 . Conclusion. Noninvasive high-frequency ventilation is effective in the treatment of RDS, and compared with the CPAP ventilation mode, it can reduce CO2 retention, increase the oxygenation index, and reduce time of operation and length of hospital stay in children with RDS. It is worthy of clinical promotion and application.
Highlights
Neonatal respiratory distress syndrome (NRDS) is a common severe lung disease in the neonatal period
A total of 74 children with NRDs who met the inclusion criteria were divided into noninvasive high-frequency group (NHFV group, 36 children) and noninvasive positive pressure ventilation group (NCPAP group, 38 children), of which there were 42 males and 32 females, with a ratio of 1.3 to 1.0
All were lower than the NCPAP group, and the differences were statistically significant; see Tables 1 and 2
Summary
Neonatal respiratory distress syndrome (NRDS) is a common severe lung disease in the neonatal period. It has the highest incidence and high mortality in preterm infants and requires respiratory support and intensive monitoring. For this reason, the key to solving this problem is to find a method that can improve clinical symptoms to effectively control the further deterioration of the disease [1]. We retrospectively analyzed children with neonatal respiratory distress syndrome who were hospitalized in hospital. Reconstruction Algorithm of Chest X-Ray e ordered subset maximum expectation method is an iterative image reconstruction algorithm developed based on the maximum likelihood expectation method (ML-EM). e traditional ML-EM is calculated as f(k)(i, j) f(k− 1)(i, j) n,mp(i, j, n, m)
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