Abstract

Retinoblastoma is a malignancy of the retina. It is most common intraocular tumor in children. Dominantly inherited disorder frequently found association with defect in RB1 gene. Approximately 40% of patients with retinoblastoma have inherited a germ-line mutation of the RB1 gene found 10% unilaterally while 60% are non-familial. Herewith we present 2 cases of non-familial, unilateral retinoblastoma.

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