Non‐oestrogen therapy of the menopausal syndrome

Abstract

AbstractA double‐blind study of cyclofenil plus diazepam compared to placebo was carried out in 30 postmenopausal patients at the Gynaecologic Clinic of São Paulo University Medical School. All patients had had amenorrhoea for at least one year before the trial. Kupperman Menopausal Index (KMI), FSH, LH, prolactin and oestradiol blood levels and vaginal smears were the data analysed.Cyclofenil 400 mg plus diazepam 10 mg po daily was the prescribed standard dose, which relieved the main symptoms of the menopausal syndrome. With the dose schedule used, neither blood hormone levels nor vaginal smears data showed any statistical difference before and after treatment. Also, no important side‐effects were observed.