Abstract
PurposeWarm ischemia (WI) and bleeding constitute the main challenges for surgeons during laparoscopic partial nephrectomy (LPN). Current literature on the use of lasers for cutting and coagulation remains scarce and with small cohorts. We present the largest case series to date of non-ischemic LPN using a diode laser for small exophytic renal tumors.MethodsWe retrospectively evaluated 29 patients with clinically localized exophytic renal tumors who underwent non-ischemic laser–assisted LPN with a 1318-nm wavelength diode laser. We started applying the laser 5 mm beyond the visible tumor margin, 5 mm away from the tissue in a non-contact fashion for coagulation and in direct contact with the parenchymal tissue for cutting. ResultsThe renal vessels were not clamped, resulting in a WIT (warm ischaemic time) of 0 min, except for one case that required warm ischemia for 12 min and parenchymal sutures. No transfusion was needed, with a mean Hemoglobin drop of 1,4 mg/dl and no postoperative complications. The eGFR did not significantly change by 6 months. Histologically, the majority of lesions (n = 22/29) were renal-cell carcinoma stage pT1a. The majority of malignant lesions (n = 13/22) had a negative margin. However, margin interpretation was difficult in 9 cases due to charring of the tumor base. A mean follow-up of 1.8 years revealed no tumor recurrence. The mean tumor diameter was 19.4 mm.ConclusionThe 1318-nm diode laser has the advantages of excellent cutting and sealing properties when applied to small vessels in the renal parenchyma, reducing the need for parenchymal sutures. However, excessive smoke, charring of the surgical margin, and inability to seal large blood vessels are encountered with this technique.
Highlights
Renal cell carcinoma is one of the more frequent carcinomas, comprising 2–3% of all cancers
As different types of lasers have already been tested, the aim of this study was to show the feasibility of laser laparoscopic partial nephrectomy (LLPN) using a 1318-nm diode laser
The diagnosis of Small renal masses (SRM) and decision for surgery with laparoscopic laser enucleation was based on CT scans and/or magnetic resonance tomography
Summary
Renal cell carcinoma is one of the more frequent carcinomas, comprising 2–3% of all cancers. [4] Patients who already suffer a chronic renal insufficiency have the highest risk to loose further renal function due to WIT. The interruption of renal blood flow leads to WIT, with a loss of renal function. In these patients, hypoxic radicals formed in the hypoxic tissue after off clamping can lead to further damage within 5–8 min. [7] With laparoscopic access, the intraoperative blood loss is lower than with the open surgical approach, whereas the postoperative complications do not increase. Smoke building and carbonization of the tissue is observed [11]
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