Abstract
Firefly luciferase (FLuc)-based in vivo optical imaging technology exerts the non-invasive monitoring of transplanted cells in experimental animal models. This chapter introduces an established cell line that stably expresses a retrovirus-delivered FLuc protein gene. The stable expression does not affect the cell morphology, proliferation, migration, and invasion abilities of the parental cells. After implantation, the bioluminescence signal of FLuc cells truly reflects cell proliferation and survival in vivo, which can provide a reliable method for dynamic detection of in vivo cell transplantation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
