Abstract

Article history: Received on: 04/01/2016 Revised on: 08/02/2016 Accepted on: 22/02/2016 Available online: 30/03/2016 Objective: The incidence of Candida has been on rise worldwide. Clinicians face dilemma in differentiating colonization from true candiduria. The species identification of Candida is important, as non albicans Candida species are increasing in number and more resistant to antifungal drugs. Material and methods: The present study was conducted at a tertiary care teaching hospital of North India with an aim of investigating prevalence of NAC spp. among Candida isolates from urinary tract specimens. Results: A total of 7627 urine samples were analysed in a tertiary care hospital. The Candida isolates (180) were further speciated by Gram stain, culture on sabouraud’s dextrose agar, germ tube test, sugar fermentation test. A total of 180 (2.36%) Candida species were isolated from 7627 urine samples. Among them non albicans Candida species were predominant (66.7%), compared to Candida albicans(33.3%).The rate of isolates of Candida species were more in females, 101 (56.1%) than in males 79 (43.9%). The highest isolation rates of Candida among uropathogens were found in age group above 60 years.The emergence of non-albicans Candida similar to the trends in the western countries should be a cause of concern in our country. Conclusions: NAC spp. have emerged as an important cause of urinary tract infections. Its isolation from clinical specimens can no longer be ignored as nonpathogenic isolate nor can it be dismissed as a contaminant. Proper surveillance of these fungal pathogens is important to improve quality of care in tertiary care setting.

Highlights

  • Urinary tract infections (UTIs) are amongst the most common infections in both outpatients as well as hospitalised patients (Rashedmarandi et al, 2008)

  • Among them non albicans Candida species were predominant (66.7%), compared to Candida albicans(33.3%).The rate of isolates of Candida species were more in females, 101 (56.1%) than in males 79 (43.9%)

  • The highest isolation rates of Candida among uropathogens were found in age group above 60 years.The emergence of non-albicans Candida similar to the trends in the western countries should be a cause of concern in our country

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Summary

Introduction

Urinary tract infections (UTIs) are amongst the most common infections in both outpatients as well as hospitalised patients (Rashedmarandi et al, 2008). The frequency of urinary tract infections (UTIs) due to Candida species is increasing and these infections are being the most common clinical finding, in hospitalised patients (Manisha et al, 2011). Candida species account for almost 10-15% nosocomial UTIs (Lundstrom et al, 2001; Kauffman et al, 2000). The presence of Candida species in the urine is known as candiduria. Candiduria if not properly diagnosed and treated has been source of morbidity and mortality (Manjunath et al, 2011). Non albicans Candida (NAC) species have replaced Candida albicans as the

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