Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: practical applications.

Gianluca Villa,On Behalf Of The Nomenclature Standardization Initiative (Nsi) Alliance ,Didier Payen,Patrick M Honore,John Kellum,Jorge Cerda,Jean-Louis Vincent,Francesco Garzotto,Claudio Ronco,Zaccaria Ricci,Julia Wendon,Anna Lorenzin,A Raffaele De Gaudio,Marta Zaccaria,Silvia De Rosa,Rinaldo Bellomo,Mauro Neri,Sara Samoni

doi:10.1186/s13054-016-1456-5

Abstract

This article reports the conclusions of the second part of a consensus expert conference on the nomenclature of renal replacement therapy (RRT) techniques currently utilized to manage acute kidney injury and other organ dysfunction syndromes in critically ill patients. A multidisciplinary approach was taken to achieve harmonization of definitions, components, techniques, and operations of the extracorporeal therapies. The article describes the RRT techniques in detail with the relevant technology, procedures, and phases of treatment and key aspects of volume management/fluid balance in critically ill patients. In addition, the article describes recent developments in other extracorporeal therapies, including therapeutic plasma exchange, multiple organ support therapy, liver support, lung support, and blood purification in sepsis. This is a consensus report on nomenclature harmonization in extracorporeal blood purification therapies, such as hemofiltration, plasma exchange, multiple organ support therapies, and blood purification in sepsis.

Highlights

The use of renal replacement therapy (RRT) in the management of acute kidney injury (AKI) requires a multidisciplinary approach
We review the practical applications of transmembrane solute and fluid transport principles and the control mechanisms for RRT devices
The article focuses on continuous renal replacement therapies (CRRTs), which are commonly used in the treatment of critically ill patients

Summary

Introduction

The use of renal replacement therapy (RRT) in the management of acute kidney injury (AKI) requires a multidisciplinary approach. It is, essential that all members of the team use the same terminology, but the terms used to describe the different modalities of RRT often vary and can be confusing. The article focuses on continuous renal replacement therapies (CRRTs), which are commonly used in the treatment of critically ill patients. We hope that this standardized terminology will be adopted by all involved in this field, including industry as they develop new devices

Methods

Conclusion