Abstract

Abstract Recently, a tricyclic receptor capable of binding a carboxylic acid or an amine has been described. A kinetic study of the reaction between benzoic acid and benzylamine to give the amide bond using this heterocyclic receptor has been performed. The results suggest that the receptor plays a significant role in accelerating the amide bond-formation. To gain further information on the complex formation between the host, benzoic acid and benzylamine, NOESY and T-ROESY experiments were performed.

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