Abstract
The nitrogen oxide content (Feno, ppb) was assessed in 113 people, with 26 healthy individuals (the control group), 64 patients with asthma, and 23 patients with COPD. Among the patients with asthma, 10 had mild disease severity, 50 had moderate disease severity and 4 had severe asthma. Twenty patients had both asthma and COPD. The results of the study demonstrated that Feno depends on a number of factors in asthma sufferers: i. Disease severity, with patients with moderate and severe asthma having much higher Feno values than patients with mild asthma ii. Disease phase, with Feno values being significantly higher during asthma exacerbation than during asthma remission iii. Responsiveness to treatment, with patients with difficult-to-treat asthma demonstrating significantly higher Feno values. Patients with COPD displayed low Feno levels, which were significantly lower than in asthma patients. Patients with COPD had low Feno levels even with a high cellular sputum content, which indicates significant airway inflammation.
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