Abstract
This review synthesized studies on sex determination, scientific basis, approaches, and achievements in sex reversal of giant freshwater prawn (GFP) (Macrobrachium rosenbergii) around the world. GFP has a ZW sex determination system, where sex chromosomes are homozygous (ZZ) in males and heterozygous (ZW) in females. Sex differentiation of this species is controlled by protein-like hormone of the androgen gland. Males whose androgen gland is ablated (andrectomy) or in-activated by using RNA interference (RNAi) will develop to neo-females. Mating of these neo-females with normal males produces monosex males. These approaches have been applied successfully in commercial farming of GFP. However, the use of artificial hormone such as 17 α-methyltestosterol was not successful in sex reversal of GFP.
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