Abstract
Summary This is the final article of a series of three. After briefly recapitulating the first two, this article will move on to consider the sources of malignant disease in the real world: diet and the bowel flora are important in this context. We will then look at some of the intermediate stages between carcinogenesis and the appearance of frank malignancy—here the topological order of DNA and oncogenes are important. Insight into natural resistance to carcinogenic influences can be gained from the study of congenital DNA repair syndromes. We will then look in more detail at the nature of these DNA repair systems and the ways in which it is possible to stimulate them. From such understanding effective therapy may evolve.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
