Abstract

Objectives: Nephrolithiasis is a disease with a high prevalence in industrialised countries. The most frequent form is calcium nephrolithiasis (80%), leading to the formation of either calcium oxalate (CaOx) or calcium phosphate (CaP) stones. Uric acid nephrolithiasis has a prevalence of about 8% of all stones, although mixed calcium–uric acid stones are frequent. High urinary uric acid excretion is a relevant lithogenic risk factor both for patients with uric acid stones and for patients with calcium stones.

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