Abstract
Abstract: Funicular myelosis (Lichtheim syndrome) is a rare neurological disorder associated with vitamin B12 deficiency, often concurrent with pernicious anemia. This deficiency is typically due to malabsorption issues in the digestive tract, particularly prevalent among the elderly population. Vitamin B12 plays a crucial role in various metabolic processes, including DNA synthesis, hematopoiesis, and neurological function. Here, we present a case study of a 73-year-old patient with severe acquired B12 deficiency anemia, hemolytic jaundice, glossitis, and funicular myelosis. The patient exhibited pronounced motor and sensory deficits, which significantly improved following treatment with cyanocobalamin. We highlight the clinical features, diagnostic considerations, and therapeutic outcomes of this case, emphasizing the importance of early recognition and intervention in B12 deficiency-related neurological disorders.
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