Abstract
New Inroads Into Our Understanding of the Tauopathies, Alzheimer's Disease, and the Contribution of Altered Protein Conformation to Human Neurological Disease.
Highlights
Departments of Neurology, Neuroscience and Ophthalmology, LSU Health Sciences Center New Orleans, Louisiana State University, New Orleans, LA, United States
A substantial scientific advance has recently been made in the elucidation of the molecular mechanism by which unusually folded, self-associating tau proteins drive the neuropathology of several common types of human neurodegenerative disease
Each of the tauopathies are defined by the progressive accumulation in the brain of microtubule-associated protein tau (MAPT) proteins as complex, multi-component fibrillar aggregates, and their incidence and prevalence correlate strongly with the degree of dementia (Shi et al, 2021; Vaquer-Alicea et al, 2021)
Summary
Departments of Neurology, Neuroscience and Ophthalmology, LSU Health Sciences Center New Orleans, Louisiana State University, New Orleans, LA, United States. A substantial scientific advance has recently been made in the elucidation of the molecular mechanism by which unusually folded, self-associating tau proteins drive the neuropathology of several common types of human neurodegenerative disease.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.