Progress in Alzheimer’s and Parkinson’s Diseases

Abstract

Pathology in Alzheimer's Disease: General: 1. The Pathogenesis of Alzheimer's Disease R.D. Terry. 2. Molecular and Cellular Abnormalities of Tau in Early Alzheimer's Disease P. Davis, et al. Apoliprotein E: 3. ApoE and Memory in Alzheimer's Disease H.S. Soininen, P.J. Riekkinen, Sr. 4. Divergent Metabolism of Apolipoproteins E3 and E4 by Cells R.E. Pitas, et al. 5. APP, ApoE, and Presenilin Transgenics: Toward a Genetic Model of Alzheimer's Disease L. Pradier, et al. Apoptosis Oxidative Stress Amyloids, Inflammation and Other Defects: 8. Apoptosis in Alzheimer's Disease: Inductive Agents and Antioxidant Protective Factors C.W. Cotman, C.J. Pike. 9. Membrane Constituencies and Receptor Subtype Contribute to Age-Related Increases in Vulnerability to Oxidative Stress: Implications for Neurodegenerative Disease J.A. Joseph, et al. 10. Mitochondrial Dysfunction and Alzheimer's Disease S.S. Ghosh, et al. 11. Mitochondrial Dysfunction in Parkinson's Disease: Potential Applications for Cybrid Modeling of the Disease R.H. Swerdlow, et al. Amyloid Aggregation: 27. Amyloid-beta Hypothesis of Alzheimer's Disease M.S. Shearman. 28. Discovery and Characterization of Peptidoorganic Inhibitors of Amyloid beta-Peptide Polymerization M.A. Findeis, S.M. Molineaux. 29. Anthracyclines and Amyloidosis C. Post, et al. 30. The Amino Terminus of the beta-Amyloid Peptide Contains an Essential Epitope for Maintaining Its Solubility B. Solomon, et al. 31. Animal Models of Amyloid Aggregation and Deposition R. Kisilevsky Tau in Alzheimer's Disease: 32. The Conformations of Tau Protein and Its Aggregation into Alzheimers Paired Helical Filaments E. Mandelkow, et al. Alzheimer's Disease/Parkinsons's Disease and Related Disorders: Clinical and Etiological Aspects: 37. Different Cognitive Profiles on Memory Tests in Parkinson's Disease and Alzheimer's Disease R.F. Allegri, et al. Parkinson's Disease--Etiology, Genetics, Treatment: 56. Genetic Aspects of Parkinson's Disease Y. Mizuno, et al. Cholinergic Strategies in Alzheimer's and Parkinson's Disease: 64. The Rationale for Development of Cholinergic Therapies in AD A. Enz, P.T. Francis. Alzheimer's Disease--Muscarinic Treatment and Therapy--beta-Amyloids: 70. APP Localization and Trafficking in the Central Nervouse System J.D. Buxbaum, et al. Cholinesterase Inhibitors for Treatment of Alzheimer's Disease: 75. Crystallographic Studies on Complexes of Acetylcholinesterase with the Natural Cholinesterase Inhibitors Fasciculin and Huperzine A I. Silman, et al. Neurotrophic Factor Therapy--Neuroprotection, Neurotransplantation and Other Treatment Strategies: 86. Functional Effects of GDNF on Dopamine Neurons in Animal Models of Parkinson's Disease A.F. Hoffman, et al. Animal Models in Alzheimer's and Parkinson's Diseases: 93. Age Dependence of Muscarinic Plasticity in the Rat Hippocampus J.M. Auerbach, M. Segal. Diagnostic Too