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Abstract
Two new abietane diterpenoids, ramentoxide ( 1) and ramentoxidone ( 2) and a new icetexane diterpenoid, amentonone ( 3) were isolated from the barks of Amentotaxus formosana. The structures of 1– 3 were determined by spectroscopic methods. Known compounds brevitaxin ( 4), and (+)-ferruginol ( 5) and ent-kaur-16-en-15-one ( 6) isolated from this plant revealed potent cytotoxic activity against human breast adenocarcinoma cells, MCF-7 cells with an IC 50 value of 0.08 ± 0.05 μg/mL, and significant anti-inflammatory activities, respectively.
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