Abstract

Fast axonal transport carries a constant stream of organelles through the axoplasm at velocities of up to 400 mm day −1 . Ever since the discovery of fast axonal transport, there has been speculation about the molecular mechanisms that move materials within the axon. However, experimental data about the mechanisms was limited. Recently, information about the properties of the fast transport system has been obtained using techniques such as microinjection, cell permeabilization, video microscopy and new ultrastructural methods. Although the mechanism of transport has not yet been identified, an understanding of the mechanism appears to be dose at hand.

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