Abstract
The management of full thickness articular cartilage defects is a challenging problem for orthopaedic surgeons. It has limited potential for healing and can be a significant source of pain and loss of function. Multiple cartilage repair strategies have been attempted. Matrix-induced Autologous Chondrocyte Implantation (MACI) has been shown to produce hyaline-like cartilage into chondral defects. The goal of this review is to provide the current principles and technique of the MACI procedure along with reported clinical outcomes with its use.
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