Abstract
In experiments conducted on white rats neurotropic action of soy lecithin, known as a source of unsaturated fatty acid s on the background of the neurotoxic impact of CCl 4 was studied QUOTE . Useage of CCl 4 by courses QUOTE showed a significant inhibitory effect that affected the spontaneous behavior of rats “in the open field” by significant inhibition of mo bility (44 - 77%), research activity (81%) and increased emotionality (140%). Such usage of soy lecithin having anti-oxidant activity and membrane-stabilizing effect led to optimization of spontaneous behavior of rats. Th e infringement of cognitive function is , possibly , due to the prooxydative effect of CCl 4 QUOTE and decrease in the unsaturated fatty acid fraction in the structure of the brain lipids. L evel of research , mink instinct, emotion ality , vertical mobility were restored, and horizontal mobility even increased by 59%. Thus, soy lecithin may be recommended as a drug with correcting cognitive brain function.
Highlights
Neurotropic action of soy lecithin in the process of cognitive function formation in white rats
Romanenko L.A. In experiments conducted on white rats neurotropic action of soy lecithin
Useage of CCl4 by courses showed a significant inhibitory effect that affected the spontaneous behavior of rats
Summary
Neurotropic action of soy lecithin in the process of cognitive function formation in white rats. Ɋɟɝɭɥɹɰɢɹ ɚɤɬɢɜɧɨɫɬɢ ɨɬɞɟɥɶɧɵɯ ɦɟɞɢɚɬɨɪɧɵɯ ɫɢɫɬɟɦ ɦɨɡɝɚ ɷɮɮɟɤɬɢɜɧɨ ɤɨɪɪɟɝɢɪɭɟɬ ɢɧɬɟɝɪɚɬɢɜɧɭɸ ɞɟɹɬɟɥɶɧɨɫɬɶ ɐɇɋ, ɜ ɱɚɫɬɧɨɫɬɢ, ɫɩɨɧɬɚɧɧɭɸ ɩɨɜɟɞɟɧɱɟɫɤɭɸ ɚɤɬɢɜɧɨɫɬɶ, ɷɦɨɰɢɨɧɚɥɶɧɨɫɬɶ, ɤɨɝɧɢɬɢɜɧɭɸ ɮɭɧɤɰɢɸ [9]. Ɂɫɫɥɟɞɭɟɦɵɟ ɩɨɤɚɡɚɬɟɥɢ ɪɟɝɢɫɬɪɢɪɨɜɚɥɢ ɩɟɪɟɞ ɧɚɱɚɥɨɦ, ɧɚ 3, 7 ɢ 14 ɫɭɬɤɢ ɷɤɫɩɟɪɢɦɟɧɬɚ ɭ ɤɨɧɬɪɨɥɶɧɵɯ ɠɢɜɨɬɧɵɯ ɢ ɤɪɵɫ, ɤɨɬɨɪɵɦ ɟɠɟɞɧɟɜɧɨ ɜɧɭɬɪɢɠɟɥɭɞɨɱɧɨ ɜɜɨɞɢɥɢ 20% ɜɡɜɟɫɶ ɫɨɟɜɨɝɨ ɥɟɰɢɬɢɧɚ (ɋɅ). Ɑɪɟɡɦɟɪɧɚɹ ɢɧɬɟɧɫɢɮɢɤɚɰɢɹ ɩɪɨɰɟɫɫɨɜ ɉɈɅ, ɦɨɠɟɬ ɩɪɢɜɨɞɢɬɶ ɤ ɫɧɢɠɟɧɢɸ ɤɨɥɢɱɟɫɬɜɚ ɉɇɀɄ ɜ ɫɬɪɭɤɬɭɪɟ ɦɟɦɛɪɚɧɧɵɯ ɥɢɩɢɞɨɜ ɦɨɡɝɚ ɢ, ɤɚɤ ɪɟɡɭɥɶɬɚɬ, ɤ ɧɚɪɭɲɟɧɢɸ ɫɢɫɬɟɦɵ ɝɨɦɟɨɜɹɡɤɨɫɬɢ ɤɥɟɬɨɱɧɵɯ ɦɟɦɛɪɚɧ [3].
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