Abstract
Neurorehabilitation in Stroke: The Role of Functional Connectivity
Highlights
In the last decade, important progress has been made with regard to clinical recovery in patients with disabling neurological conditions such as ischemic and hemorrhagic stroke
These findings suggest that cortical stimulation may be a promising approach to improve synaptic dysfunction and functional reorganization of motor networks after stroke, enhancing clinical recovery [2]
A successful motor recovery produced by conventional physiotherapy, robot-assisted therapy, or transcranial magnetic stimulation over the motor cortex is likely mediated by cortical network reorganization
Summary
Important progress has been made with regard to clinical recovery in patients with disabling neurological conditions such as ischemic and hemorrhagic stroke. Despite the advancement in neurointerventional surgery and medical treatment options (e.g., tissue plasminogen activator) applied within a few hours of stroke onset, stroke remains the main cause of permanent disability in Europe and the USA [2]. Rehabilitative interventions such as intensive physiotherapy, neuropsychological rehabilitation or application of cutting-edge technologies, including robot-assisted therapy are associated with a high degree of physical and cognitive recovery. The analysis of functional connectivity can help us to understand the effect of stroke on cerebral networks and why some patients make a better recovery than others [4]. The aim of this work is to discuss the potential role of functional connectivity and brain network reorganization in predicting neurorehabilitation outcomes after stroke
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