Neuropsychiatric Disorders Revealing Autoimmune Polyendocrine Syndrome Type 3: Case Report

Abstract

Multiple autoimmune syndrome is a rare pathological condition because it associates at least three different autoimmune diseases in the same patient. We discuss through this case and with a review of the literature MAS type 3 and its association with neuroanemic syndrome which remains exceptional. This is a 47-year-old patient, followed for vitiligo and a depressive syndrome, admitted for an ataxic gait lasting a month, in whom the neurological examination revealed a combined sclerosis syndrome of the spinal cord associated with a static cerebellar syndrome. Dermatological examination revealed diffuse acrofacial vitiligo. The biological assessment revealed Biermer's anemia and autoimmune thyroiditis. The clinical evolution was favorable under treatment. The discovery of Biermer's disease in a woman should prompt the search for arguments for one or other associated autoimmune diseases.