Abstract

neuropattern: a translational tool to reduce stress in the workplace Objectives: The study assesses the usefulness of a novel translational tool, neuropattern, in the prevention of stress-related disorders by means of personalised diagnostics and treatment measures derived therefrom. It took the form of a pilot study with a wait list control group. Methods: 70 employees of the Forestry Department Rhineland-Palatinate in Germany were assigned to an experimental group or a wait list control group by means of block randomisation and underwent neuropattern diagnostics either immediately at the start of the study or after a waiting period of three months. After the diagnostic assessment, all study participants received an explanatory disease model and access to individualised online self-help, whilst their physicians were provided with a diagnostic report and treatment recommendations. Questionnaires on health (SF-12), stress perception (PSS), emotional exhaustion (MBI), work-related stress (ERI), work ability (WAI) and health behaviour were used at the start of the study and after three months in order to assess possible beneficial effects of neuropattern. Results: Compared to the control group, the application of neuropattern in the experimental group resulted in a greater improvement in mental health, a significant increase in sporting activity and a significantly higher reduction in perceived stress, emotional exhaustion, overexertion and burnout in the workplace. No significant differences were found with regard to the development of physical health, current work ability, work-related reward, effort-reward ratio and practice of relaxation methods. Contrary to expectations, it was possible to observe growing pessimism about future work ability and a higher increase in sick leave in the experimental group as compared to the control group. Conclusions: The present study delivers initial findings on the usefulness of neuropattern diagnostics in a non-clinical population. However, further research is required to determine the best operating conditions. Keywords: work-related stress – burnout – prevention – conceptual endophenotypes – personalised medicine – neuropattern

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