Abstract
The neuronal doctrine, which shaped the development of neuroscience, was born from a long-lasting struggle between reticularists, who assumed internal continuity of neural networks and neuronists, who defined the brain as a network of physically separated cellular entities, defined as neurones. Modern views regard the brain as a complex of constantly interacting cellular circuits, represented by neuronal networks embedded into internally connected astroglial syncytium. The neuronal-glial circuits endowed with distinct signalling cascades form a 'diffuse nervous net' suggested by Golgi, where millions of synapses belonging to very different neurones are integrated first into neuronal-glial-vascular units and then into more complex structures connected through glial syncytium. These many levels of integration, both morphological and functional, presented by neuronal-glial circuitry ensure the spatial and temporal multiplication of brain cognitive power.
Published Version
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