Abstract
To investigate the relationship between serum NSE and welders' pneumoconiosis, through chest X-ray and serum NSE. The exposed group included 37 welders. The non-exposed group included 38 administrative workers. Both groups underwent history taking, clinical examination, chest X-ray, serum chromium and serum neuron-specific enolase (NSE). Air sampling was done for total suspended particles (TSP), respirable particles (PM10) and welding fumes (WFs). All the air samples were within the national TLVs. Chest X-ray abnormalities were found in 8 welders (21.6%), and included reticular opacities, scattered nodules or ground glass opacities (GGOs). Serum chromium and NSE were significantly higher among welders. Serum NSE correlated positively with the duration of exposure, and serum chromium level among welders. Serum NSE can be used as a biomarker for early detection of welders' pneumoconiosis.
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