Abstract
Takotsubo syndrome (TTS, apical ballooning, stress cardiomyopathy, transient left ventricular dysfunction, broken heart syndrome) is characterised by a reversible mid-segmental left ventricular dysfunction of which the pathogenesis remains speculative but which is said to be due to enhanced central or focal sympathetic stimulation, triggered by emotional or physical stress [ 1 Porto I. Della Bona R. Leo A. et al. Stress cardiomyopathy (tako-tsubo) triggered by nervous system diseases: a systematic review of the reported cases. Int J Cardiol. 2013; 167: 2441-2448 Abstract Full Text Full Text PDF PubMed Scopus (51) Google Scholar , 2 Tsuchihashi K. Ueshima K. Uchida T. et al. Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris–Myocardial Infarction Investigations in Japan. J Am Coll Cardiol. 2001; 38: 11-18 Abstract Full Text Full Text PDF PubMed Scopus (1336) Google Scholar ]. TTS has been occasionally reported in association with neuromuscular disorders (NMDs) but it is unclear how frequently TTS is associated with NMDs and which types of NMDs are associated with TTS. Aim of this literature search was to investigate how frequently TTS is associated with a NMD, which MIDs have been described in association with TTS, and if NMDs contribute to the pathogenesis of TTS.
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