Abstract
The progression of diabetes has been linked with disruption of the microvascular system, which may lead to other degenerative conditions, including diabetic nephropathy, cardiomyopathy, and neuropathy. Cognitive dysfunction has been linked with diabetes-induced neurodegeneration. Changes in metabolic processes, including disruption of inflammatory pathways, cholinergic function, purinergic processes, and neurotransmitters triggered by chronic hyperglycemia, may affect brain function. Hence, the need to explore novel biomarkers to identify the risk of neurological deficit and impairment in the central nervous system in diabetic conditions. This chapter thoroughly reviewed the recently published articles on the biochemical mechanisms and biomarkers associated with diabetic encephalopathy and neuroinflammation. The roles of the biomarkers involved in diabetic encephalopathy will provide novel insights on possible therapeutic interventions that can mitigate cognitive problems and neurological dysfunction associated with chronic hyperglycemia as well as diabetes mellitus.KeywordsDiabetesDiabetic encephalopathyCognitive impairmentNeuroinflammationCholinergic dysfunction
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
