Abstract
Primary neuroendocrine tumours of the breast are rare. The WHO has classified them according to the tissue grading. The clinical presentation is similar to the usual infiltrating ductal carcinomas, however the histopathological assessment requires special staining to confirm the diagnosis of neuroendocrine tumour. We report a case of a primary neuroendocrine tumour of the breast in a 33-year-old lady who presented with a locally advanced breast tumour with multicentric disease.
 Bangladesh Journal of Medical Science Vol.18(2) 2019 p.419-422
Highlights
Neuroendocrine tumour is rare; primary neuroendocrine tumour (NET) of the breast is even rarer
Recent immunohistochemical studies revealed that some typical infiltrating ductal carcinoma (IDC) of the breast show areas of neuroendocrine differentiation, primary neuroendocrine tumours with lymph node involvement are still extremely uncommon[2,3]
We describe a case of primary NET of the breast in a young lady and its subsequent management
Summary
Neuroendocrine tumour is rare; primary neuroendocrine tumour (NET) of the breast is even rarer. Primary NET of the breast has features similar to NET of the gastrointestinal tract and lung. They present clinically with a breast mass and is often wrongly diagnosed as infiltrating ductal carcinoma (IDC) from a core biopsy resulting in less effective neoadjuvant or adjuvant treatment regime.
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