Abstract
This study examined the behavioral effects of caffeine, measured in cord blood and saliva, on infant behavior. In order to examine these effects, 40 full-term, healthy, vaginally delivered, breast-fed neonates and their healthy, nonsmoking mothers were studied. A nutritional questionnaire was developed and given to each participating mother to determine her approximate caffeine intake during the last three days before delivery. For each infant subject, cord blood samples from delivery and saliva samples taken on the day of behavioral testing were assayed for caffeine. Statistical analyses revealed a significant effect of caffeine level on certain interactive behaviors in response to stimulation but little or no observed effect upon spontaneous sleep states.
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