Neoplasias das glândulas salivares minor - Estudo retrospectivo

Abstract

Objectives: Descriptive analysis of cases of neoplasms of minor salivary glands treated in Otolaryngology Service Institute of Lisbon, and compares the results with what is described in the literature.Methods: Retrospective analysis of all cases with histological diagnosis of cancer of the minor salivary glands of the nasal cavity, oral cavity, larynx and pharynx, which occurred during the period from October 1992 to November 2015, treated at the ENT service of the Portuguese Institute Oncology Lisbon Francisco Gentil.Results: 58 cases of cancer of the minor salivary glands were documented, 60% occurred in females and 40% were male, with a mean age of 57 years. The most frequent symptom in the nasal cavity was nasal obstruction, in the oral cavity was the presence of ulcers or swelling, and oropharyngeal was pain. The most common histologic types were adenoid cystic carcinoma (33%) polymorphic adenocarcinoma (24%) and mucoepidermoid carcinoma (22%). The oropharynx was the most common location of these tumours. The surgery was the treatment of 1st line in 93% of cases and 52% had adjuvant radiotherapy. Recurrence occurred in 20% of cases. The mortality associated with the tumour was 7%.Conclusions: Neoplasms of the minor salivary glands are rare, the most common being the adenoid cystic carcinoma, pleomorphic adenocarcinoma and mucoepidermoid carcinoma. Surgical treatment alone is effective in many cases. Mortality is related to the stage and histological type of tumour.