Abstract
s1 April 1964Neonatal Unconjugated Hyperbilirubinemia Associated with Breast-feeding and a Steroid in Milk That Inhibits Glucuronide Formation in Vitro.Irwin M. Arias, M.D., Mathilda Furman, Lawrence M. Gartner, Ph.D., Sam Seifter, Ph.D.Irwin M. Arias, M.D.Search for more papers by this author, Mathilda FurmanSearch for more papers by this author, Lawrence M. Gartner, Ph.D.Search for more papers by this author, Sam Seifter, Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-4-724_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSix unrelated 2-week-old breast-fed infants who were clinically well had serum unconjugated bilirubin concentrations of 15.0 to 24.3 mg/100 ml not due to known causes. The hyperbilirubinemia disappeared within 5 days after cessation of breast-feeding in five infants. The sixth infant alternated breast and artificial feeding and became anicteric 12 days later at 4 weeks of age. The mothers had breast-fed five previous children, four of whom had unexplained and prolonged jaundice. Breast milk obtained from these women strongly inhibited the formation of O-aminophenol glucuronide and direct-reacting bilirubin by rat, guinea pig, and rabbit liver homogenates and microsomes in vitro.... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, New York PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1964Volume 60, Issue 4Page: 724-724KeywordsAttentionBilirubinBreast feedingBreast milkChildrenGuinea pigsInfantsLiverMilkRabbits Issue Published: 1 April 1964 PDF DownloadLoading ...
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