Abstract
Objective: To screen newborns for congenital hypothyroidism by time resolved fluoroimmunoassay (TRFIA) (TRFIA meter by Perkin Elmer). Methods: Participants were randomly selected from the Department of Paediatrics/Obstetrics and Gynaecology, Rajendra Institute of Medical Sciences and Maternity Hospitals around 20 km of Rajendra Institute of Medical Sciences, Ranchi. Blood samples were obtained by heel prick for thyroid-stimulating hormone (TSH) estimation from newborns selected from abovementioned hospitals. Samples were collected from 3rd day of life to 7th day of life on a filter paper card and analyzed by TRFIAbased method. Results: 60% of the newborns were male and 40% were female among 150 newborns selected for study. Out ofthem, 65.33% were term, 28% were pre-term, and 6.67% were post-term. 92% newborns had TSH level 20 mIU/L. Conclusion: The prevalence of borderline TSH assay was 80/1000 newborns, which is significant. Screening studies for such conditions need larger sample size, stronger logistics to cover a larger area.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
