Abstract
A 4-year neonatal screening for infantile hypothyroidism (IH) performed in the Moscow Region in 1995—1998 under relevant Federal program has detected 29 neonates with IH. The cases distribution in the Region was sporadic with the mean frequency of 1:6286. By the incidence of retesting, 53 districts of Moscow region were grouped into 3 groups (Pl, P2, P3), differing by the functional activity of the thyroid. The incidence of retests was significantly higher in P3 region vs. P2 and P3 regions (РЗ > P2 > P3) and correlated with the incidence of transitory hypothyrosis and published data on high level of technogenic pollution of the territories, and presence of markers of ecology-related diseases. Epidemiological values of neonatal screening for congenital hypothyrosis indicate that iodine deficiency in the Moscow region can be regarded as characteristic moderately severe.
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