Abstract
Introduction: Neoadjuvant endocrine therapy (NAET) is increasingly being used in the management of oestrogen receptor positive (ER+) breast cancer (BC). Little is known about the rate of complete response, optimal method(s) for histological assessment of response to NAET, and the effect of the therapy on the histological characteristics and receptor status of the tumours. This study aims to assess the histological features of response to NAET and its effect on tumour type, grade and molecular profile.
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