Abstract

Wound Healing As reported by Joo H. Kang and co-workers in article number 2211149, implantable vascularized engineered thrombi (IVET) using autologous blood can improve wound healing by creating robust microcapillary networks. By aligning fibrin fibers and activating platelets through microfluidic shear stress, the engineered thrombi create a moderate stiffness microenvironment that can promote endothelial cell maturation and vascularization. In full-thickness skin wound models, IVET implantation facilitates rapid and scar-free wound recovery.

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